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DRESS is a T-cell-mediated adverse drug reaction characterised by widespread rash with or without eosinophilia, fevers, lymphadenopathy and organ involvement (most commonly kidney or liver injury). Identifying the culprit drug can be problematic in patients receiving multiple medicines. Doses above 2 mg/kg (or in excess of 200 mg) once daily have not been studied in pediatric patients. Even small doses can precipitate another reaction so desensitisation is contraindicated. Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in non-lactating women and in early postpartum women. However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment in postpartum mothers. However, it is common for allopurinol to set off painful flares of gout in the first months after starting it.<br><br><br> However, it is especially common among young adults who struggle with mental health conditions. 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